Settings are generally at three different levels:

Application settings such as visible decimal places,
Project Options such as unit preferences, and
Scenario Options that you may want to change for different scenarios.

Performance improvement can be important for large models. Explore settings that can help with this under Improving Performance.

Source graphs can be customised both individually and globally, from the Recording Manager or by choosing Tools » User Chart Settings.... Refer to Customising chart views for further detail.

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